Toxicology of Organophosphate Carbamate Compounds by Ramesh C. Gupta
Toxicology of Organophosphate Carbamate Compounds Ramesh C. Gupta ebook
ISBN: 0120885239, 9780120885237
Publisher: Academic Press
Butterworth Heinemann: Oxford; 1992. In health, agriculture, and government, the word “organophosphates” refers to a group of insecticides or nerve agents acting on the enzyme acetylcholinesterase (the pesticide group carbamates also act on this enzyme, but through a different mechanism). It is extremely toxic to non target organisms like fish and hampers fish health through impairment .. Prolonged administration of sublethal doses of organophosphorus cholinesterase inhibitors results in adaptation to their toxicity. Clinical and Experimental Toxicology of Organophosphates and Carbamates. A locally manufactured carbamate poison with 90% methomyl inside. The term is used often to describe virtually any organic phosphorus(V)-containing compound, especially when dealing with neurotoxic compounds. Pralidoxime is the oxime most often .. Many of the so-called organophosphates contain C-P bonds. The patient's toxicology screen was negative for ethanol, benzodiazepines, barbiturates, cocaine metabolites, cannabinoids, opiates and amphetamine like compounds. The clinical effects due to carbamates are of shorter duration than those observed with organophosphorus compounds. Among the wide majority of pesticides, dichlorvos (2, 2-dichlorovinyl dimethyl phosphate), a organophosphate compound, is commonly used as agricultural insecticide. (1962) Toxicity of certain organophosphorus and carbamate insecticides to rainbow trout. Despite their known toxicity to oncology patients and the precautionary measures taken to prevent occupational exposure, a number of workers from different disciplines could be exposed to significant concentrations of cytostatic drugs during their . In : Pesticides studied in man. LD50 of tabun sc poisonings with organophosphorus compounds (OPCs), including OP insecticides (OPIs) and nerve agents tabun . A second class of compounds-oximes, capable of regenerating the active enzyme from the OP-cholinesterase complex, is also available to treat OP poisoning. In order to investigate this phenomenon, we exposed rats to 0.2, 0.3 or 0.4.
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